Americans who have trouble getting prescriptions from doctors for narcotic medications often find no problem accessing the drugs from illicit online sites.
It will be more difficulty under a crackdown led by ICE and the Department of Justice, which have seized 686 websites accused of selling fake or illegal drug over the past week, ICE said in a press release.
The initiative, called Bitter Pill, was designed to disrupt crime networks peddling illegal online drugs.
Bitter Pill involves 100 countries and netted 79 arrests and the seizure of nearly 4 million doses of counterfeit medications.